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The Role of Vitamin D in Thyroid Diseases.

Abstract The main role of vitamin D is regulating bone metabolism and calcium and phosphorus homeostasis. Over the past few decades, the importance of vitamin D in non-skeletal actions has been studied, including the role of vitamin D in autoimmune diseases, metabolic syndromes, cardiovascular disease, cancers, and all-cause mortality. Recent evidence has demonstrated an association between low vitamin D status and autoimmune thyroid diseases such as Hashimoto's thyroiditis and Graves' disease, and impaired vitamin D signaling has been reported in thyroid cancers. This review will focus on recent data on the possible role of vitamin D in thyroid diseases, including autoimmune thyroid diseases and thyroid cancers.
PMID
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Authors

Mayor MeshTerms
Keywords

Graves’ disease

Hashimoto’s thyroiditis

autoimmune thyroid disease

thyroid cancer

vitamin D

Journal Title international journal of molecular sciences
Publication Year Start




PMID- 28895880
OWN - NLM
STAT- In-Process
DA  - 20170912
LR  - 20170912
IS  - 1422-0067 (Electronic)
IS  - 1422-0067 (Linking)
VI  - 18
IP  - 9
DP  - 2017 Sep 12
TI  - The Role of Vitamin D in Thyroid Diseases.
LID - E1949 [pii]
LID - 10.3390/ijms18091949 [doi]
AB  - The main role of vitamin D is regulating bone metabolism and calcium and
      phosphorus homeostasis. Over the past few decades, the importance of vitamin D in
      non-skeletal actions has been studied, including the role of vitamin D in
      autoimmune diseases, metabolic syndromes, cardiovascular disease, cancers, and
      all-cause mortality. Recent evidence has demonstrated an association between low 
      vitamin D status and autoimmune thyroid diseases such as Hashimoto's thyroiditis 
      and Graves' disease, and impaired vitamin D signaling has been reported in
      thyroid cancers. This review will focus on recent data on the possible role of
      vitamin D in thyroid diseases, including autoimmune thyroid diseases and thyroid 
      cancers.
FAU - Kim, Dohee
AU  - Kim D
AD  - Division of Endocrinology, Department of Internal Medicine, Dankook University
      College of Medicine, Dandae-ro, Dongnam-gu, Cheonan-si, Chungnam 330-714, Korea. 
      [email protected]
AD  - Department of Kinesiologic Medical Science, Graduate, Dankook University, Cheonan
      330-714, Korea. [email protected]
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20170912
PL  - Switzerland
TA  - Int J Mol Sci
JT  - International journal of molecular sciences
JID - 101092791
OTO - NOTNLM
OT  - Graves' disease
OT  - Hashimoto's thyroiditis
OT  - autoimmune thyroid disease
OT  - thyroid cancer
OT  - vitamin D
COI - The author declares no conflict of interest.
EDAT- 2017/09/13 06:00
MHDA- 2017/09/13 06:00
CRDT- 2017/09/13 06:00
PHST- 2017/07/14 [received]
PHST- 2017/09/06 [revised]
PHST- 2017/09/07 [accepted]
AID - ijms18091949 [pii]
AID - 10.3390/ijms18091949 [doi]
PST - epublish
SO  - Int J Mol Sci. 2017 Sep 12;18(9). pii: E1949. doi: 10.3390/ijms18091949.