Is Stand-Alone Anterior Lumbar Interbody Fusion a Safe and Efficacious Treatment for Isthmic Spondylolisthesis of L5-S1?
|Abstract||A systematic review.|
Comparison of instrumented posterolateral fusion versus percutaneous pedicle screw fixation combined with anterior lumbar interbody fusion in elderly patients with L5-S1 isthmic spondylolisthesis and foraminal stenosis.
|Journal Title||global spine journal|
|Publication Year Start||2017-01-01|
PMID- 28894689 OWN - NLM STAT- PubMed-not-MEDLINE DA - 20170912 LR - 20170914 IS - 2192-5682 (Print) IS - 2192-5682 (Linking) VI - 7 IP - 6 DP - 2017 Sep TI - Is Stand-Alone Anterior Lumbar Interbody Fusion a Safe and Efficacious Treatment for Isthmic Spondylolisthesis of L5-S1? PG - 587-595 LID - 10.1177/2192568217699210 [doi] AB - STUDY DESIGN: A systematic review. OBJECTIVE: The objective of this study was to determine the safety and efficacy of stand-alone anterior lumbar interbody fusion (sa-ALIF) for the treatment of symptomatic isthmic spondylolisthesis of L5-S1 by assessing the level of available clinical and radiographic evidence. METHODS: A systematic review utilizing Medline, Embase, and Scopus online databases was undertaken. Clinical, radiographic, and adverse outcome data were extracted for the relevant isthmic spondylolisthesis cases with the intention of undertaking a meta-analysis. RESULTS: The database search between January 1980 and December 2015 yielded 23 articles that concerned sa-ALIF for isthmic spondylolisthesis of L5-S1. Only in 9 of the 23 articles data could be extracted specific to sa-ALIF for isthmic spondylolisthesis of L5-S1. There was considerable inconsistency in the standards for reporting outcomes of the surgery due to which meta-analysis could not be undertaken, and hence each article was reviewed. CONCLUSIONS: There was insufficient evidence to support the safety and efficacy of sa-ALIF for the treatment of isthmic spondylolisthesis of L5-S1. Although sa-ALIF is widely documented in the literature, there was insufficient evidence to support its use in treating this specific pathology. The unique pathological and anatomical situation that isthmic spondylolisthesis of L5-S1 presents must be recognized and its treatment with sa-ALIF should be well thought out. FAU - Viglione, Luke L AU - Viglione LL AD - Spine Service, St. George & Sutherland Clinical School, The University of New South Wales, Kogarah, New South Wales, Australia. FAU - Chamoli, Uphar AU - Chamoli U AD - Spine Service, St. George & Sutherland Clinical School, The University of New South Wales, Kogarah, New South Wales, Australia. AD - School of Mechanical & Manufacturing Engineering, Kensington campus, The University of New South Wales, Sydney, New South Wales, Australia. FAU - Diwan, Ashish D AU - Diwan AD AD - Spine Service, St. George & Sutherland Clinical School, The University of New South Wales, Kogarah, New South Wales, Australia. LA - eng PT - Journal Article PT - Review DEP - 20170601 PL - England TA - Global Spine J JT - Global spine journal JID - 101596156 PMC - PMC5582709 OTO - NOTNLM OT - anterior lumbar interbody fusion OT - low back pain OT - lumbar interbody fusion OT - pars interarticularis defect OT - spondylolisthesis COI - Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. EDAT- 2017/09/13 06:00 MHDA- 2017/09/13 06:01 CRDT- 2017/09/13 06:00 AID - 10.1177/2192568217699210 [doi] AID - 10.1177_2192568217699210 [pii] PST - ppublish SO - Global Spine J. 2017 Sep;7(6):587-595. doi: 10.1177/2192568217699210. Epub 2017 Jun 1.