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Heart Failure Due to Reduced Ejection Fraction: Medical Management.

Abstract Heart failure is an increasingly common condition resulting in high rates of morbidity and mortality. For patients who have heart failure and reduced ejection fraction, randomized clinical trials demonstrate consistent mortality benefit from angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, direct-acting vasodilators, beta blockers, and aldosterone antagonists. Additionally, some data show benefits from two new classes of drugs: angiotensin receptor blocker/neprilysin inhibitor and sinus node modulator. Diuretics and digoxin can be used as needed for symptom control. Statins are not recommended solely for treatment of heart failure. Implantable cardioverter-defibrillators and biventricular pacemakers improve mortality and function in selected patients. For patients who have been hospitalized for heart failure, disease management programs and telemonitoring can reduce hospitalizations and mortality.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title american family physician
Publication Year Start




PMID- 28075105
OWN - NLM
STAT- In-Data-Review
DA  - 20170111
LR  - 20170112
IS  - 1532-0650 (Electronic)
IS  - 0002-838X (Linking)
VI  - 95
IP  - 1
DP  - 2017 Jan 01
TI  - Heart Failure Due to Reduced Ejection Fraction: Medical Management.
PG  - 13-20
AB  - Heart failure is an increasingly common condition resulting in high rates of
      morbidity and mortality. For patients who have heart failure and reduced ejection
      fraction, randomized clinical trials demonstrate consistent mortality benefit
      from angiotensin-converting enzyme inhibitors, angiotensin receptor blockers,
      direct-acting vasodilators, beta blockers, and aldosterone antagonists.
      Additionally, some data show benefits from two new classes of drugs: angiotensin 
      receptor blocker/neprilysin inhibitor and sinus node modulator. Diuretics and
      digoxin can be used as needed for symptom control. Statins are not recommended
      solely for treatment of heart failure. Implantable cardioverter-defibrillators
      and biventricular pacemakers improve mortality and function in selected patients.
      For patients who have been hospitalized for heart failure, disease management
      programs and telemonitoring can reduce hospitalizations and mortality.
FAU - Chavey, William E
AU  - Chavey WE
AD  - University of Michigan Health System, Ann Arbor, MI, USA.
FAU - Hogikyan, Robrt V
AU  - Hogikyan RV
AD  - University of Michigan Health System, Ann Arbor, MI, USA.
FAU - Van Harrison, R
AU  - Van Harrison R
AD  - University of Michigan Health System, Ann Arbor, MI, USA.
FAU - Nicklas, John M
AU  - Nicklas JM
AD  - University of Michigan Health System, Ann Arbor, MI, USA.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Am Fam Physician
JT  - American family physician
JID - 1272646
EDAT- 2017/01/12 06:00
MHDA- 2017/01/12 06:00
CRDT- 2017/01/12 06:00
AID - d12850 [pii]
PST - ppublish
SO  - Am Fam Physician. 2017 Jan 1;95(1):13-20.

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