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Characteristics of Children Aged <18 Years with Zika Virus Disease Acquired Postnatally - U.S. States, January 2015-July 2016.

Abstract Zika virus is an emerging mosquito-borne flavivirus that typically causes an asymptomatic infection or mild illness, although infection during pregnancy is a cause of microcephaly and other serious brain abnormalities. Guillain-Barré syndrome and other neurologic complications can occur in adults after Zika virus infection. However, there are few published reports describing postnatally acquired Zika virus disease among children. During January 2015-July 2016, a total of 158 cases of confirmed or probable postnatally acquired Zika virus disease among children aged <18 years were reported to CDC from U.S. states. The median age was 14 years (range = 1 month-17 years), and 88 (56%) were female. Two (1%) patients were hospitalized; none developed Guillain-Barré syndrome, and none died. All reported cases were travel-associated. Overall, 129 (82%) children had rash, 87 (55%) had fever, 45 (29%) had conjunctivitis, and 44 (28%) had arthralgia. Health care providers should consider a diagnosis of Zika virus disease in children who have an epidemiologic risk factor and clinically compatible illness, and should report cases to their state or local health department.
PMID
Related Publications

Update: Ongoing Zika Virus Transmission - Puerto Rico, November 1, 2015-April 14, 2016.

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Local Transmission of Zika Virus--Puerto Rico, November 23, 2015-January 28, 2016.

Travel-Associated Zika Virus Disease Cases Among U.S. Residents--United States, January 2015-February 2016.

Zika Virus Disease Cases - 50 States and the District of Columbia, January 1-July 31, 2016.

Authors

Mayor MeshTerms
Keywords
Journal Title mmwr. morbidity and mortality weekly report
Publication Year Start




PMID- 27711041
OWN - NLM
STAT- In-Data-Review
DA  - 20161006
LR  - 20161007
IS  - 1545-861X (Electronic)
IS  - 0149-2195 (Linking)
VI  - 65
IP  - 39
DP  - 2016 Oct 07
TI  - Characteristics of Children Aged &lt;18 Years with Zika Virus Disease Acquired
      Postnatally - U.S. States, January 2015-July 2016.
PG  - 1082-1085
LID - 10.15585/mmwr.mm6539e2 [doi]
AB  - Zika virus is an emerging mosquito-borne flavivirus that typically causes an
      asymptomatic infection or mild illness, although infection during pregnancy is a 
      cause of microcephaly and other serious brain abnormalities. Guillain-Barre
      syndrome and other neurologic complications can occur in adults after Zika virus 
      infection. However, there are few published reports describing postnatally
      acquired Zika virus disease among children. During January 2015-July 2016, a
      total of 158 cases of confirmed or probable postnatally acquired Zika virus
      disease among children aged &lt;18 years were reported to CDC from U.S. states. The 
      median age was 14 years (range = 1 month-17 years), and 88 (56%) were female. Two
      (1%) patients were hospitalized; none developed Guillain-Barre syndrome, and none
      died. All reported cases were travel-associated. Overall, 129 (82%) children had 
      rash, 87 (55%) had fever, 45 (29%) had conjunctivitis, and 44 (28%) had
      arthralgia. Health care providers should consider a diagnosis of Zika virus
      disease in children who have an epidemiologic risk factor and clinically
      compatible illness, and should report cases to their state or local health
      department.
FAU - Goodman, Alyson B
AU  - Goodman AB
FAU - Dziuban, Eric J
AU  - Dziuban EJ
FAU - Powell, Krista
AU  - Powell K
FAU - Bitsko, Rebecca H
AU  - Bitsko RH
FAU - Langley, Gayle
AU  - Langley G
FAU - Lindsey, Nicole
AU  - Lindsey N
FAU - Franks, Jessica L
AU  - Franks JL
FAU - Russell, Kate
AU  - Russell K
FAU - Dasgupta, Sharoda
AU  - Dasgupta S
FAU - Barfield, Wanda D
AU  - Barfield WD
FAU - Odom, Erika
AU  - Odom E
FAU - Kahn, Emily
AU  - Kahn E
FAU - Martin, Stacey
AU  - Martin S
FAU - Fischer, Marc
AU  - Fischer M
FAU - Staples, J Erin
AU  - Staples JE
LA  - ENG
PT  - JOURNAL ARTICLE
DEP - 20161007
PL  - United States
TA  - MMWR Morb Mortal Wkly Rep
JT  - MMWR. Morbidity and mortality weekly report
JID - 7802429
EDAT- 2016/10/07 06:00
MHDA- 2016/10/07 06:00
CRDT- 2016/10/07 06:00
AID - 10.15585/mmwr.mm6539e2 [doi]
PST - epublish
SO  - MMWR Morb Mortal Wkly Rep. 2016 Oct 7;65(39):1082-1085. doi:
      10.15585/mmwr.mm6539e2.

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