PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.
%A Wu, Emily S.; Oduyebo, Titilope; Cobb, Lauren P.; Cholakian, Diana; Kong, Xiangrong; Fader, Amanda N.; Levinson, Kimberly L.; Tanner, Edward J.; Stone, Rebecca L.; Piotrowski, Anna; Grossman, Stuart; Long Roche, Kara
%T Lymphopenia and its association with survival in patients with locally advanced cervical cancer.
%J Gynecologic oncology, vol. 140, no. 1, pp. 76-82
%D 01/2016
%V 140
%N 1
%M eng
%B To evaluate the association between lymphopenia and survival in women with cervical cancer treated with primary chemoradiation.
%K Adult, Chemoradiotherapy, Disease-Free Survival, Female, Humans, Kaplan-Meier Estimate, Lymphopenia, Middle Aged, Neoplasm Staging, Prognosis, Retrospective Studies, Uterine Cervical Neoplasms
%P 76
%L 82
%Y 10.1016/j.ygyno.2015.11.013
%W PHY
%G AUTHOR
%R 2016......140...76W

@Article{Wu2016,
author="Wu, Emily S.
and Oduyebo, Titilope
and Cobb, Lauren P.
and Cholakian, Diana
and Kong, Xiangrong
and Fader, Amanda N.
and Levinson, Kimberly L.
and Tanner, Edward J.
and Stone, Rebecca L.
and Piotrowski, Anna
and Grossman, Stuart
and Long Roche, Kara",
title="Lymphopenia and its association with survival in patients with locally advanced cervical cancer.",
journal="Gynecologic oncology",
year="2016",
month="Jan",
day="11",
volume="140",
number="1",
pages="76--82",
keywords="Adult",
keywords="Chemoradiotherapy",
keywords="Disease-Free Survival",
keywords="Female",
keywords="Humans",
keywords="Kaplan-Meier Estimate",
keywords="Lymphopenia",
keywords="Middle Aged",
keywords="Neoplasm Staging",
keywords="Prognosis",
keywords="Retrospective Studies",
keywords="Uterine Cervical Neoplasms",
abstract="To evaluate the association between lymphopenia and survival in women with cervical cancer treated with primary chemoradiation.",
issn="1095-6859",
doi="10.1016/j.ygyno.2015.11.013",
url="http://www.ncbi.nlm.nih.gov/pubmed/26571200",
language="eng"
}

%0 Journal Article
%T Lymphopenia and its association with survival in patients with locally advanced cervical cancer.
%A Wu, Emily S.
%A Oduyebo, Titilope
%A Cobb, Lauren P.
%A Cholakian, Diana
%A Kong, Xiangrong
%A Fader, Amanda N.
%A Levinson, Kimberly L.
%A Tanner, Edward J.
%A Stone, Rebecca L.
%A Piotrowski, Anna
%A Grossman, Stuart
%A Long Roche, Kara
%J Gynecologic oncology
%D 2016
%8 Jan 11
%V 140
%N 1
%@ 1095-6859
%G eng
%F Wu2016
%X To evaluate the association between lymphopenia and survival in women with cervical cancer treated with primary chemoradiation.
%K Adult
%K Chemoradiotherapy
%K Disease-Free Survival
%K Female
%K Humans
%K Kaplan-Meier Estimate
%K Lymphopenia
%K Middle Aged
%K Neoplasm Staging
%K Prognosis
%K Retrospective Studies
%K Uterine Cervical Neoplasms
%U http://dx.doi.org/10.1016/j.ygyno.2015.11.013
%U http://www.ncbi.nlm.nih.gov/pubmed/26571200
%P 76-82

PT Journal
AU Wu, ES
   Oduyebo, T
   Cobb, LP
   Cholakian, D
   Kong, X
   Fader, AN
   Levinson, KL
   Tanner, EJ
   Stone, RL
   Piotrowski, A
   Grossman, S
   Long Roche, K
TI Lymphopenia and its association with survival in patients with locally advanced cervical cancer.
SO Gynecologic oncology
JI Gynecol. Oncol.
PD Jan
PY 2016
BP 76
EP 82
VL 140
IS 1
DI 10.1016/j.ygyno.2015.11.013
LA eng
DE Adult; Chemoradiotherapy; Disease-Free Survival; Female; Humans; Kaplan-Meier Estimate; Lymphopenia; Middle Aged; Neoplasm Staging; Prognosis; Retrospective Studies; Uterine Cervical Neoplasms
AB To evaluate the association between lymphopenia and survival in women with cervical cancer treated with primary chemoradiation.
ER

PMID- 26571200
OWN - NLM
STAT- MEDLINE
DA  - 20160103
DCOM- 20160428
LR  - 20160309
IS  - 1095-6859 (Electronic)
IS  - 0090-8258 (Linking)
VI  - 140
IP  - 1
DP  - 2016 Jan
TI  - Lymphopenia and its association with survival in patients with locally advanced
      cervical cancer.
PG  - 76-82
LID - 10.1016/j.ygyno.2015.11.013 [doi]
LID - S0090-8258(15)30185-2 [pii]
AB  - OBJECTIVE: To evaluate the association between lymphopenia and survival in women 
      with cervical cancer treated with primary chemoradiation. METHODS: A single
      institution, retrospective analysis of patients with stage IB2-IVA cervical
      cancer who received upfront chemoradiation from 1998 to 2013 was performed.
      Complete blood counts from pre-treatment to 36 months post-treatment were
      analyzed. Lymphopenia and known prognostic factors were evaluated for an
      association with progression-free (PFS) and overall survival (OS). RESULTS:
      Seventy-one patients met study criteria for whom 47 (66%) had a documented total 
      lymphocyte count (TLC) two months after initiating chemoradiation. FIGO stage
      distribution was 6% Stage I, 46% Stage II, 45% Stage III and 3% Stage IV.
      Pre-treatment TLC was abnormal (<1000 cells/mm3) in 15% of patients. The mean
      reduction in TLC was 70% two months after initiating chemoradiation. Severe
      post-treatment lymphopenia (TLC <500 cells/mm3) was observed in 53% of patients; 
      they experienced inferior median OS (21.2 vs. 45.0 months, P=0.03) and similar
      25th percentile PFS (6.3 vs. 7.7 months, P=0.06) compared to patients without
      severe lymphopenia. Multivariate analysis demonstrated pre-treatment TLC >/=1000 
      cells/mm3 and post-treatment TLC >500 cells/mm3 had a 77% (HR: 0.23; 95% CI
      0.05-1.03; P=0.053) and 58% decrease in hazards of death (HR: 0.42; 95%CI
      0.12-1.46; P=0.17) respectively. CONCLUSION: More than half of cervical cancer
      patients treated with chemoradiation experienced severe and prolonged
      lymphopenia. Although statistical significance was not reached, the findings
      suggest that pre- and post-treatment lymphopenia may be associated with decreased
      survival. Further research is warranted, given that lymphopenia could be a
      reversible prognostic factor.
CI  - Copyright (c) 2015 Elsevier Inc. All rights reserved.
FAU - Wu, Emily S
AU  - Wu ES
AD  - Kelly Gynecologic Oncology Service, Department of Gynecology and Obstetrics,
      Johns Hopkins Hospital, Baltimore, MD, USA. Electronic address: [email protected]
FAU - Oduyebo, Titilope
AU  - Oduyebo T
AD  - Department of Epidemiology, Johns Hopkins Hospital School of Public Health,
      Baltimore, MD, USA.
FAU - Cobb, Lauren P
AU  - Cobb LP
AD  - Kelly Gynecologic Oncology Service, Department of Gynecology and Obstetrics,
      Johns Hopkins Hospital, Baltimore, MD, USA.
FAU - Cholakian, Diana
AU  - Cholakian D
AD  - Kelly Gynecologic Oncology Service, Department of Gynecology and Obstetrics,
      Johns Hopkins Hospital, Baltimore, MD, USA.
FAU - Kong, Xiangrong
AU  - Kong X
AD  - Department of Epidemiology, Johns Hopkins Hospital School of Public Health,
      Baltimore, MD, USA.
FAU - Fader, Amanda N
AU  - Fader AN
AD  - Kelly Gynecologic Oncology Service, Department of Gynecology and Obstetrics,
      Johns Hopkins Hospital, Baltimore, MD, USA.
FAU - Levinson, Kimberly L
AU  - Levinson KL
AD  - Kelly Gynecologic Oncology Service, Department of Gynecology and Obstetrics,
      Johns Hopkins Hospital, Baltimore, MD, USA.
FAU - Tanner, Edward J 3rd
AU  - Tanner EJ 3rd
AD  - Kelly Gynecologic Oncology Service, Department of Gynecology and Obstetrics,
      Johns Hopkins Hospital, Baltimore, MD, USA.
FAU - Stone, Rebecca L
AU  - Stone RL
AD  - Kelly Gynecologic Oncology Service, Department of Gynecology and Obstetrics,
      Johns Hopkins Hospital, Baltimore, MD, USA.
FAU - Piotrowski, Anna
AU  - Piotrowski A
AD  - The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University,
      Baltimore, MD, USA.
FAU - Grossman, Stuart
AU  - Grossman S
AD  - The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University,
      Baltimore, MD, USA.
FAU - Long Roche, Kara
AU  - Long Roche K
AD  - Kelly Gynecologic Oncology Service, Department of Gynecology and Obstetrics,
      Johns Hopkins Hospital, Baltimore, MD, USA.
LA  - eng
GR  - P30 CA006973/CA/NCI NIH HHS/United States
PT  - Journal Article
DEP - 20151111
PL  - United States
TA  - Gynecol Oncol
JT  - Gynecologic oncology
JID - 0365304
SB  - IM
MH  - Adult
MH  - Chemoradiotherapy
MH  - Disease-Free Survival
MH  - Female
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - Lymphopenia/*pathology
MH  - Middle Aged
MH  - Neoplasm Staging
MH  - Prognosis
MH  - Retrospective Studies
MH  - Uterine Cervical Neoplasms/*blood/drug therapy/radiotherapy/*therapy
PMC - PMC4782779
MID - NIHMS763246
OID - NLM: NIHMS763246
OID - NLM: PMC4782779
OTO - NOTNLM
OT  - Cervical cancer
OT  - Chemoradiation
OT  - Lymphopenia
EDAT- 2015/11/17 06:00
MHDA- 2016/04/29 06:00
CRDT- 2015/11/17 06:00
PHST- 2015/10/02 [received]
PHST- 2015/11/06 [revised]
PHST- 2015/11/08 [accepted]
PHST- 2015/11/11 [aheadofprint]
AID - S0090-8258(15)30185-2 [pii]
AID - 10.1016/j.ygyno.2015.11.013 [doi]
PST - ppublish
SO  - Gynecol Oncol. 2016 Jan;140(1):76-82. doi: 10.1016/j.ygyno.2015.11.013. Epub 2015
      Nov 11.

<?xml version="1.0" encoding="UTF-8"?>
<b:Sources SelectedStyle="" xmlns:b="http://schemas.openxmlformats.org/officeDocument/2006/bibliography"  xmlns="http://schemas.openxmlformats.org/officeDocument/2006/bibliography" >
<b:Source>
<b:Tag>Wu2016</b:Tag>
<b:SourceType>ArticleInAPeriodical</b:SourceType>
<b:Year>2016</b:Year>
<b:Month>Jan</b:Month>
<b:Day>11</b:Day>
<b:PeriodicalName>Gynecologic oncology</b:PeriodicalName>
<b:Volume>140</b:Volume>
<b:Issue>1</b:Issue>
<b:Pages>76-82</b:Pages>
<b:Author>
<b:Author><b:NameList>
<b:Person><b:Last>Wu</b:Last><b:First>Emily</b:First><b:Middle>S</b:Middle></b:Person>
<b:Person><b:Last>Oduyebo</b:Last><b:First>Titilope</b:First></b:Person>
<b:Person><b:Last>Cobb</b:Last><b:First>Lauren</b:First><b:Middle>P</b:Middle></b:Person>
<b:Person><b:Last>Cholakian</b:Last><b:First>Diana</b:First></b:Person>
<b:Person><b:Last>Kong</b:Last><b:First>Xiangrong</b:First></b:Person>
<b:Person><b:Last>Fader</b:Last><b:First>Amanda</b:First><b:Middle>N</b:Middle></b:Person>
<b:Person><b:Last>Levinson</b:Last><b:First>Kimberly</b:First><b:Middle>L</b:Middle></b:Person>
<b:Person><b:Last>Tanner</b:Last><b:First>Edward</b:First><b:Middle>J</b:Middle></b:Person>
<b:Person><b:Last>Stone</b:Last><b:First>Rebecca</b:First><b:Middle>L</b:Middle></b:Person>
<b:Person><b:Last>Piotrowski</b:Last><b:First>Anna</b:First></b:Person>
<b:Person><b:Last>Grossman</b:Last><b:First>Stuart</b:First></b:Person>
<b:Person><b:Last>Long Roche</b:Last><b:First>Kara</b:First></b:Person>
</b:NameList></b:Author>
</b:Author>
<b:Title>Lymphopenia and its association with survival in patients with locally advanced cervical cancer.</b:Title>
 <b:ShortTitle>Gynecol. Oncol.</b:ShortTitle>
<b:Comments>To evaluate the association between lymphopenia and survival in women with cervical cancer treated with primary chemoradiation.</b:Comments>
</b:Source>
</b:Sources>