PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

Retrospective cohort study evaluating the impact of intraperitoneal morcellation on outcomes of localized uterine leiomyosarcoma.

Abstract Uterine leiomyosarcoma (ULMS) is identified in 0.1% to 0.2% of hysterectomy specimens of presumed leiomyoma. To date, there is no preoperative technique that reliably differentiates ULMS from uterine leiomyoma. Increasing use of minimally invasive approaches for the management of leiomyomas may result in inadvertently morcellated ULMS with resultant intraperitoneal dissemination of tumor. The objective of this study was to assess the impact of intraperitoneal morcellation on the outcomes of patients with ULMS.
PMID
Related Publications

Risk Factors for Occult Uterine Sarcoma Among Women Undergoing Minimally Invasive Gynecologic Surgery.

The impact of tumor morcellation during surgery on the prognosis of patients with apparently early uterine leiomyosarcoma.

Technical update on tissue morcellation during gynaecologic surgery: its uses, complications, and risks of unsuspected malignancy.

Impact of morcellation on survival outcomes of patients with unexpected uterine leiomyosarcoma: a systematic review and meta-analysis.

The value of re-exploration in patients with inadvertently morcellated uterine sarcoma.

Authors

Mayor MeshTerms
Keywords

hysterectomy

morcellation

outcomes

uterine leiomyosarcoma

uterine sarcoma

Journal Title cancer
Publication Year Start
%A George, Suzanne; Barysauskas, Constance; Serrano, C?sar; Oduyebo, Titilope; Rauh-Hain, Jose A.; Del Carmen, Marcela G.; Demetri, George D.; Muto, Michael G.
%T Retrospective cohort study evaluating the impact of intraperitoneal morcellation on outcomes of localized uterine leiomyosarcoma.
%J Cancer, vol. 120, no. 20, pp. 3154-3158
%D 10/2014
%V 120
%N 20
%M eng
%B Uterine leiomyosarcoma (ULMS) is identified in 0.1% to 0.2% of hysterectomy specimens of presumed leiomyoma. To date, there is no preoperative technique that reliably differentiates ULMS from uterine leiomyoma. Increasing use of minimally invasive approaches for the management of leiomyomas may result in inadvertently morcellated ULMS with resultant intraperitoneal dissemination of tumor. The objective of this study was to assess the impact of intraperitoneal morcellation on the outcomes of patients with ULMS.
%K Adult, Aged, Cohort Studies, Female, Gynecologic Surgical Procedures, Humans, Leiomyosarcoma, Middle Aged, Minimally Invasive Surgical Procedures, Prognosis, Retrospective Studies, Treatment Outcome, Uterine Neoplasms
%P 3154
%L 3158
%Y 10.1002/cncr.28844
%W PHY
%G AUTHOR
%R 2014CaRes.120.3154G

@Article{George2014,
author="George, Suzanne
and Barysauskas, Constance
and Serrano, C{\'e}sar
and Oduyebo, Titilope
and Rauh-Hain, Jose A.
and Del Carmen, Marcela G.
and Demetri, George D.
and Muto, Michael G.",
title="Retrospective cohort study evaluating the impact of intraperitoneal morcellation on outcomes of localized uterine leiomyosarcoma.",
journal="Cancer",
year="2014",
month="Oct",
day="15",
volume="120",
number="20",
pages="3154--3158",
keywords="Adult",
keywords="Aged",
keywords="Cohort Studies",
keywords="Female",
keywords="Gynecologic Surgical Procedures",
keywords="Humans",
keywords="Leiomyosarcoma",
keywords="Middle Aged",
keywords="Minimally Invasive Surgical Procedures",
keywords="Prognosis",
keywords="Retrospective Studies",
keywords="Treatment Outcome",
keywords="Uterine Neoplasms",
abstract="Uterine leiomyosarcoma (ULMS) is identified in 0.1\% to 0.2\% of hysterectomy specimens of presumed leiomyoma. To date, there is no preoperative technique that reliably differentiates ULMS from uterine leiomyoma. Increasing use of minimally invasive approaches for the management of leiomyomas may result in inadvertently morcellated ULMS with resultant intraperitoneal dissemination of tumor. The objective of this study was to assess the impact of intraperitoneal morcellation on the outcomes of patients with ULMS.",
issn="1097-0142",
doi="10.1002/cncr.28844",
url="http://www.ncbi.nlm.nih.gov/pubmed/24923260",
language="eng"
}

%0 Journal Article
%T Retrospective cohort study evaluating the impact of intraperitoneal morcellation on outcomes of localized uterine leiomyosarcoma.
%A George, Suzanne
%A Barysauskas, Constance
%A Serrano, C?sar
%A Oduyebo, Titilope
%A Rauh-Hain, Jose A.
%A Del Carmen, Marcela G.
%A Demetri, George D.
%A Muto, Michael G.
%J Cancer
%D 2014
%8 Oct 15
%V 120
%N 20
%@ 1097-0142
%G eng
%F George2014
%X Uterine leiomyosarcoma (ULMS) is identified in 0.1% to 0.2% of hysterectomy specimens of presumed leiomyoma. To date, there is no preoperative technique that reliably differentiates ULMS from uterine leiomyoma. Increasing use of minimally invasive approaches for the management of leiomyomas may result in inadvertently morcellated ULMS with resultant intraperitoneal dissemination of tumor. The objective of this study was to assess the impact of intraperitoneal morcellation on the outcomes of patients with ULMS.
%K Adult
%K Aged
%K Cohort Studies
%K Female
%K Gynecologic Surgical Procedures
%K Humans
%K Leiomyosarcoma
%K Middle Aged
%K Minimally Invasive Surgical Procedures
%K Prognosis
%K Retrospective Studies
%K Treatment Outcome
%K Uterine Neoplasms
%U http://dx.doi.org/10.1002/cncr.28844
%U http://www.ncbi.nlm.nih.gov/pubmed/24923260
%P 3154-3158

PT Journal
AU George, S
   Barysauskas, C
   Serrano, C
   Oduyebo, T
   Rauh-Hain, JA
   Del Carmen, MG
   Demetri, GD
   Muto, MG
TI Retrospective cohort study evaluating the impact of intraperitoneal morcellation on outcomes of localized uterine leiomyosarcoma.
SO Cancer
PD Oct
PY 2014
BP 3154
EP 3158
VL 120
IS 20
DI 10.1002/cncr.28844
LA eng
DE Adult; Aged; Cohort Studies; Female; Gynecologic Surgical Procedures; Humans; Leiomyosarcoma; Middle Aged; Minimally Invasive Surgical Procedures; Prognosis; Retrospective Studies; Treatment Outcome; Uterine Neoplasms
AB Uterine leiomyosarcoma (ULMS) is identified in 0.1% to 0.2% of hysterectomy specimens of presumed leiomyoma. To date, there is no preoperative technique that reliably differentiates ULMS from uterine leiomyoma. Increasing use of minimally invasive approaches for the management of leiomyomas may result in inadvertently morcellated ULMS with resultant intraperitoneal dissemination of tumor. The objective of this study was to assess the impact of intraperitoneal morcellation on the outcomes of patients with ULMS.
ER

PMID- 24923260
OWN - NLM
STAT- MEDLINE
DA  - 20141006
DCOM- 20150417
IS  - 1097-0142 (Electronic)
IS  - 0008-543X (Linking)
VI  - 120
IP  - 20
DP  - 2014 Oct 15
TI  - Retrospective cohort study evaluating the impact of intraperitoneal morcellation 
      on outcomes of localized uterine leiomyosarcoma.
PG  - 3154-8
LID - 10.1002/cncr.28844 [doi]
AB  - BACKGROUND: Uterine leiomyosarcoma (ULMS) is identified in 0.1% to 0.2% of
      hysterectomy specimens of presumed leiomyoma. To date, there is no preoperative
      technique that reliably differentiates ULMS from uterine leiomyoma. Increasing
      use of minimally invasive approaches for the management of leiomyomas may result 
      in inadvertently morcellated ULMS with resultant intraperitoneal dissemination of
      tumor. The objective of this study was to assess the impact of intraperitoneal
      morcellation on the outcomes of patients with ULMS. METHODS: In this
      retrospective cohort study, all patients with ULMS who attended the authors'
      institutions from 2007 to 2012 were reviewed. Demographics and outcomes were
      compared between those who underwent morcellation or total abdominal hysterectomy
      (TAH) as their first surgery for uterus-limited ULMS. RESULTS: In total, 58
      patients were identified, including 39 who underwent TAH and 19 who underwent
      intraperitoneal morcellation. Intraperitoneal morcellation was associated with a 
      significantly increased risk of abdominal/pelvic recurrences (P = .001) and with 
      significantly shorter median recurrence-free survival (10.8 months vs 39.6
      months; P = .002). A multivariate adjusted model demonstrated a > 3 times
      increased risk of recurrence associated with morcellation (hazard ratio, 3.18;
      95% confidence interval, 1.5-6.8; P = .003). CONCLUSIONS: Intraperitoneal
      morcellation of presumed leiomyoma worsens the outcomes of women with ULMS.
      Because there are no reliable preoperative techniques to distinguish ULMS from
      benign leiomyoma, all efforts to minimize intraperitoneal uterine morcellation
      should be considered. [See editorial on pages 000-000, this issue.]
CI  - (c) 2014 American Cancer Society.
FAU - George, Suzanne
AU  - George S
AD  - Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute, Harvard
      Medical School, Boston, Massachusetts.
FAU - Barysauskas, Constance
AU  - Barysauskas C
FAU - Serrano, Cesar
AU  - Serrano C
FAU - Oduyebo, Titilope
AU  - Oduyebo T
FAU - Rauh-Hain, Jose A
AU  - Rauh-Hain JA
FAU - Del Carmen, Marcela G
AU  - Del Carmen MG
FAU - Demetri, George D
AU  - Demetri GD
FAU - Muto, Michael G
AU  - Muto MG
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140612
PL  - United States
TA  - Cancer
JT  - Cancer
JID - 0374236
SB  - AIM
SB  - IM
CIN - Cancer. 2014 Dec 15;120(24):4004-5. PMID: 25102972
CIN - Cancer. 2014 Oct 15;120(20):3100-2. PMID: 24925689
CIN - Cancer. 2014 Dec 15;120(24):4005. PMID: 25102828
MH  - Adult
MH  - Aged
MH  - Cohort Studies
MH  - Female
MH  - Gynecologic Surgical Procedures/*instrumentation/methods
MH  - Humans
MH  - Leiomyosarcoma/pathology/*surgery
MH  - Middle Aged
MH  - Minimally Invasive Surgical Procedures/*instrumentation/methods
MH  - Prognosis
MH  - Retrospective Studies
MH  - Treatment Outcome
MH  - Uterine Neoplasms/pathology/*surgery
OTO - NOTNLM
OT  - hysterectomy
OT  - morcellation
OT  - outcomes
OT  - uterine leiomyosarcoma
OT  - uterine sarcoma
EDAT- 2014/06/14 06:00
MHDA- 2015/04/18 06:00
CRDT- 2014/06/14 06:00
PHST- 2014/02/13 [received]
PHST- 2014/04/08 [revised]
PHST- 2014/04/08 [accepted]
PHST- 2014/06/12 [aheadofprint]
AID - 10.1002/cncr.28844 [doi]
PST - ppublish
SO  - Cancer. 2014 Oct 15;120(20):3154-8. doi: 10.1002/cncr.28844. Epub 2014 Jun 12.
TY  - JOUR
AU  - George, Suzanne
AU  - Barysauskas, Constance
AU  - Serrano, C?sar
AU  - Oduyebo, Titilope
AU  - Rauh-Hain, Jose A.
AU  - Del Carmen, Marcela G.
AU  - Demetri, George D.
AU  - Muto, Michael G.
PY  - 2014/Oct/15
TI  - Retrospective cohort study evaluating the impact of intraperitoneal morcellation on outcomes of localized uterine leiomyosarcoma.
JO  - Cancer
SP  - 3154
EP  - 3158
VL  - 120
IS  - 20
KW  - Adult
KW  - Aged
KW  - Cohort Studies
KW  - Female
KW  - Gynecologic Surgical Procedures
KW  - Humans
KW  - Leiomyosarcoma
KW  - Middle Aged
KW  - Minimally Invasive Surgical Procedures
KW  - Prognosis
KW  - Retrospective Studies
KW  - Treatment Outcome
KW  - Uterine Neoplasms
N2  - Uterine leiomyosarcoma (ULMS) is identified in 0.1% to 0.2% of hysterectomy specimens of presumed leiomyoma. To date, there is no preoperative technique that reliably differentiates ULMS from uterine leiomyoma. Increasing use of minimally invasive approaches for the management of leiomyomas may result in inadvertently morcellated ULMS with resultant intraperitoneal dissemination of tumor. The objective of this study was to assess the impact of intraperitoneal morcellation on the outcomes of patients with ULMS.
SN  - 1097-0142
UR  - http://dx.doi.org/10.1002/cncr.28844
UR  - http://www.ncbi.nlm.nih.gov/pubmed/24923260
ID  - George2014
ER  - 
<?xml version="1.0" encoding="UTF-8"?>
<b:Sources SelectedStyle="" xmlns:b="http://schemas.openxmlformats.org/officeDocument/2006/bibliography"  xmlns="http://schemas.openxmlformats.org/officeDocument/2006/bibliography" >
<b:Source>
<b:Tag>George2014</b:Tag>
<b:SourceType>ArticleInAPeriodical</b:SourceType>
<b:Year>2014</b:Year>
<b:Month>Oct</b:Month>
<b:Day>15</b:Day>
<b:PeriodicalName>Cancer</b:PeriodicalName>
<b:Volume>120</b:Volume>
<b:Issue>20</b:Issue>
<b:Pages>3154-3158</b:Pages>
<b:Author>
<b:Author><b:NameList>
<b:Person><b:Last>George</b:Last><b:First>Suzanne</b:First></b:Person>
<b:Person><b:Last>Barysauskas</b:Last><b:First>Constance</b:First></b:Person>
<b:Person><b:Last>Serrano</b:Last><b:First>C&#233;sar</b:First></b:Person>
<b:Person><b:Last>Oduyebo</b:Last><b:First>Titilope</b:First></b:Person>
<b:Person><b:Last>Rauh-Hain</b:Last><b:First>Jose</b:First><b:Middle>A</b:Middle></b:Person>
<b:Person><b:Last>Del Carmen</b:Last><b:First>Marcela</b:First><b:Middle>G</b:Middle></b:Person>
<b:Person><b:Last>Demetri</b:Last><b:First>George</b:First><b:Middle>D</b:Middle></b:Person>
<b:Person><b:Last>Muto</b:Last><b:First>Michael</b:First><b:Middle>G</b:Middle></b:Person>
</b:NameList></b:Author>
</b:Author>
<b:Title>Retrospective cohort study evaluating the impact of intraperitoneal morcellation on outcomes of localized uterine leiomyosarcoma.</b:Title>
<b:Comments>Uterine leiomyosarcoma (ULMS) is identified in 0.1% to 0.2% of hysterectomy specimens of presumed leiomyoma. To date, there is no preoperative technique that reliably differentiates ULMS from uterine leiomyoma. Increasing use of minimally invasive approaches for the management of leiomyomas may result in inadvertently morcellated ULMS with resultant intraperitoneal dissemination of tumor. The objective of this study was to assess the impact of intraperitoneal morcellation on the outcomes of patients with ULMS.</b:Comments>
</b:Source>
</b:Sources>